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RIPK3 Antibody (C-term)

RIPK3 Antibody (C-term)

Item no.	ABC-AP7819B-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Receptor-interacting serine/threonine-protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3
Available
Primary Accession	Q9Y572
Other Accession	NP_006862
Antigen Type	Synthetic Peptide
Bio Background	RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Bio References	Yu, P.W., et al., Curr. Biol. 9(10):539-542 (1999). Sun, X., et al., J. Biol. Chem. 274(24):16871-16875 (1999).
Gene ID	11035
Gene Name	RIPK3 (HGNC:10021)
Reactivity	H, M
Calculated MW	56887
Antigen Region	489-518
Antigen Source	HUMAN
Target/Specificity	This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human RIPK3.
NCBI Accession	NP_006862.2

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Amount: 80 ul

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