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RAF1 (BRAF) Antibody (T598)

RAF1 (BRAF) Antibody (T598)

Item no.	ABC-AP7810k-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Signaling Antibodies Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies Astrocytoma
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1
Available
Primary Accession	P15056
Other Accession	P11345; Q99N57; P04049; P05625; A7E3S4; P28028; Q04982
Antigen Type	Synthetic Peptide
Bio Background	BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Bio References	Hingorani, S.R., et al., Cancer Res. 63(17):5198-5202 (2003). Lee, J.W., et al., Br. J. Cancer 89(10):1958-1960 (2003). Davies, H., et al., Nature 417(6892):949-954 (2002). Naoki, K., et al., Cancer Res. 62(23):7001-7003 (2002). Stephens, R.M., et al., Mol. Cell. Biol. 12(9):3733-3742 (1992).
Gene ID	673
Gene Name	BRAF
Reactivity	H
Predicted	C, M, B, Rat
Calculated MW	84437
Antigen Region	577-606
Antigen Source	HUMAN
Target/Specificity	This RAF1 (BRAF) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-606 amino acids from human RAF1 (BRAF).
NCBI Accession	NP_004324.2

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Amount: 80 ul

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