Item no. |
ABC-AP7756a |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applications |
WB, FC, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
FKBP1A, Rotamase, FKBP1, FKBP12, FKBP-12, Peptidyl-prolyl cis-trans isomerase FKBP1A, FKBP-1A, Calstabin-1, 12 kDa FK506-binding protein, Immunophilin FKBP12, 12 kDa FKBP, FK506-binding protein 1A, PPIase FKBP1A |
Available |
|
Primary Accession |
P62942 |
Antigen Type |
Synthetic Peptide |
Application |
WB, FC, IHC-P |
Bio Background |
FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. |
Bio References |
Gerard, M., J. Neurochem. 106 (1), 121-133 (2008)Shor, B., Cancer Res. 68 (8), 2934-2943 (2008)Jayaraman, T., J. Biol. Chem. 267 (14), 9474-9477 (1992) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19306 |
Gene ID |
2280 |
Gene Name |
FKBP1A |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of FKBP1A antibody (N-term) (Cat.# AP7756a) in mouse cerebellum tissue lysates, HepG2 and Jurkat cell line lysates (35ug/lane). FKBP1A (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of FKBP1A (arrow) using rabbit polyclonal FKBP1A Antibody (N-term) (Cat. #AP7756a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FKBP1A gene. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
FKBP1A Antibody (N-term) (Cat.# AP7756a) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 3 |
IHC-P |
Dilution image 3 |
1:50~100 |
Legend image 4 |
FKBP1A Antibody (N-term) (Cat. #AP7756a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 4 |
FC |
Dilution image 4 |
1:10~50 |
Other Accession |
P62943; P26883; P18203 |
Predicted |
B, Rb |
Isotype |
Rabbit Ig |
Calculated MW |
11951 |
Antigen Region |
1-30 |
Antigen Source |
HUMAN |
Target/Specificity |
This FKBP1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FKBP1A. |
NCBI Accession |
NP_000792.1; NP_463460.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.