Bio Background |
The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. |
Bio References |
Zanardi, T.A., et al., J. Virol. 77(21):11685-11696 (2003).Krug, A.W., et al., J. Biol. Chem. 278(44):43060-43066 (2003).Huang, F., et al., J. Biol. Chem. 278(44):43411-43417 (2003).He, Y.Y., et al., J. Biol. Chem. 278(43):42457-42465 (2003).Hirsch, F.R., et al., J. Clin. Oncol. 21(20):3798-3807 (2003). |
Legend image 1 |
EGFR Antibody (pY1092) (Cat.# AP7628p) western blot analysis in A431, Hela, HUVEC, PC-3 cell line lysates (35ug/lane).This demonstrates the EGFR antibody detected the EGFR protein (arrow). |