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EphA3 Antibody (N-term)

EphA3 Antibody (N-term)

Item no.	ABC-AP7608a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Myelofibrosis Immunohistochemistry Western Blot Primary Antibodies Colorectal Cancer Heart & Blood Cancer
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ephrin type-A receptor 3, EPH-like kinase 4, EK4, hEK4, HEK, Human embryo kinase, Tyrosine-protein kinase TYRO4, Tyrosine-protein kinase receptor ETK1, Eph-like tyrosine kinase 1, EPHA3, ETK, ETK1, HEK, TYRO4
Available
Primary Accession	P29320
Other Accession	P29319
Antigen Type	Synthetic Peptide
Bio Background	Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Bio References	Chiari, R., et al., Cancer Res. 60(17):4855-4863 (2000). Wicks, I.P., et al., Proc. Natl. Acad. Sci. U.S.A. 89(5):1611-1615 (1992). Boyd, A.W., et al., J. Biol. Chem. 267(5):3262-3267 (1992).
Gene ID	2042
Gene Name	EPHA3
Reactivity	H
Predicted	M
Calculated MW	110131
Antigen Region	115-144
Antigen Source	HUMAN
Target/Specificity	This EphA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human EphA3.
NCBI Accession	NP_005224.2; NP_872585.1

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Amount: 80 ul

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