Item no. |
ABC-AP7337a-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CPN1, ACBP, Carboxypeptidase N catalytic chain, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, CPN, SCPN, Serum carboxypeptidase N |
Available |
|
Primary Accession |
P15169 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
CPN1 is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The protein is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This protein is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits. |
Bio References |
Davis, D.A., Singer, K.E. Blood 105 (12), 4561-4568 (2005)Riley, D.A., Tan, F. Genomics 50 (1), 105-108 (1998)Hendriks, D., Vingron, M. Biol. Chem. Hoppe-Seyler 374 (9), 843-849 (1993) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19020 |
Gene ID |
1369 |
Gene Name |
CPN1 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
All lanes : Anti-CPN1 Antibody (N-term) at 1:1000 dilutionLane 1: human liver lysateLane 2: HepG2 whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of CPN1 antibody (N-term) (Cat.#AP7337a) in K562, CEM, HEpG2 cell line lysates and mouse liver tissue lysates (35ug/lane). CPN1(arrow) was detected using the purified Pab. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Legend image 3 |
Western blot analysis of CPN1 (arrow) using rabbit polyclonal CPN1 Antibody (N-term) (Cat. #AP7337a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CPN1 gene. |
Type image 3 |
WB |
Dilution image 3 |
1:1000 |
Isotype |
Rabbit Ig |
Calculated MW |
52286 |
Antigen Region |
52-81 |
Antigen Source |
HUMAN |
Target/Specificity |
This CPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CPN1. |
NCBI Accession |
NP_001299.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.