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GSN Antibody (N-term)

GSN Antibody (N-term)

Item no.	ABC-AP7326a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GSN, Gelsolin, Actin-depolymerizing factor, ADF, Brevin, AGEL
Available
Primary Accession	P06396
Antigen Type	Synthetic Peptide
Application	WB, FC, IHC-P
Bio Background	GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).
Bio References	Li, Q., Ye, Z. Biochem. Biophys. Res. Commun. 385 (2), 284-289 (2009) Walsh, N., Dowling, P. J Proteomics 71 (5), 561-571 (2008) Paunio, T., Kiuru, S. Genomics 13 (1), 237-239 (1992)
Clonality	Polyclonal
Clone/Animal Names	RB18721
Gene ID	2934
Gene Name	GSN
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M, Rat
Legend image 1	All lanes : Anti-GSN Antibody (N-term) at 1:1000-1:2000 dilution Lane 1: human plasma lysates Lane 2: Hela whole cell lysates Lane 3: mouse spleen lysates Lane 4: rat kidney lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 86 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000-1:2000
Legend image 2	Anti-GSN Antibody (N-term)at 1:2000 dilution + MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 86 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:2000
Legend image 3	GSN Antibody (N-term) (RB18721) IHC analysis in formalin fixed and paraffin embedded human Skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GSN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	GSN Antibody (N-term) (Cat. #AP7326a) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	Q3SX14
Predicted	B
Isotype	Rabbit Ig
Calculated MW	85698
Antigen Region	230-259
Antigen Source	HUMAN
Target/Specificity	This GSN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 amino acids from the N-terminal region of human GSN.
NCBI Accession	NP_000168.1; NP_001121134.1; NP_001121135.2; NP_001121136.1; NP_001121137.1; NP_001121138.1; NP_001121139.1; NP_001244958.1; NP_001244959.1; NP_937895.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/6/2024

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