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Aurora-C (AURKC) Antibody (C-term K255)

Aurora-C (AURKC) Antibody (C-term K255)

Item no.	ABC-AP7000b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Blastoma Carcinoma Hematology Leukemia Myeloma Melanoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Aurora kinase C, Aurora 3, Aurora/IPL1-related kinase 3, ARK-3, Aurora-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, AURKC, AIE2, AIK3, AIRK3, ARK3, STK13
Available
Primary Accession	Q9UQB9
Antigen Type	Synthetic Peptide
Bio Background	Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Bio References	Li, X., et al., J. Biol. Chem. 279(45):47201-47211 (2004). Kimura, M., et al., J. Biol. Chem. 274(11):7334-7340 (1999). Bernard, M., et al., Genomics 53(3):406-409 (1998). Tseng, T.C., et al., DNA Cell Biol. 17(10):823-833 (1998).
Gene ID	6795
Gene Name	AURKC
Reactivity	H
Calculated MW	35591
Antigen Source	HUMAN
Target/Specificity	This Aurora-C (AURKC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region with lysine at position 255 of human AURKC.
NCBI Accession	NP_001015878.1; NP_001015879.1; NP_003151.2

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Amount: 80 ul

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