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Wee1 (phospho Ser642) Polyclonal Antibody

Wee1 (phospho Ser642) Polyclonal Antibody

Item no.	ABC-AP67322
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
Available
Primary Accession	P30291
Antigen Type	synthetic peptide
Application	WB
Bio Background	Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
Clonality	Polyclonal
Gene ID	7465
Gene Name	WEE1
Reactivity	H, M, Rat
Type image 1	WB
Dilution image 1	Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 9/6/2024

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