Item no. |
ABC-AP6517b-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
FGB, Fibrinopeptide B, Fibrinogen beta chain |
Available |
|
Primary Accession |
P02675 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. |
Bio References |
Sun, A., Acta Cardiol 64 (3), 357-361 (2009)Guo, X., Neurol. Res. 31 (4), 381-384 (2009) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB19513 |
Gene ID |
2244 |
Gene Name |
FGB |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Western blot analysis of FIBB antibody (C-term) (Cat.# AP6517b) in mouse liver tissue lysates (35ug/lane). FIBB (arrow) was detected using the purified Pab. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
FIBB Antibody (C-term) (Cat.# AP6517b) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FIBB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
P14480; Q8K0E8 |
Predicted |
Rat |
Isotype |
Rabbit Ig |
Calculated MW |
55928 |
Antigen Region |
330-357 |
Antigen Source |
HUMAN |
Target/Specificity |
This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-357 amino acids from the C-terminal region of human FIBB. |
NCBI Accession |
NP_001171670.1; NP_005132.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.