Comparison

FIBB Antibody (C-term)

Item no. ABC-AP6517b-ev
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products FGB, Fibrinopeptide B, Fibrinogen beta chain
Available
Primary Accession
P02675
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Bio References
Sun, A., Acta Cardiol 64 (3), 357-361 (2009)
Guo, X., Neurol. Res. 31 (4), 381-384 (2009)
Clonality
Polyclonal
Clone/Animal Names
RB19513
Gene ID
2244
Gene Name
FGB
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Legend image 1
Western blot analysis of FIBB antibody (C-term) (Cat.# AP6517b) in mouse liver tissue lysates (35ug/lane). FIBB (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
FIBB Antibody (C-term) (Cat.# AP6517b) IHC analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FIBB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
P14480; Q8K0E8
Predicted
Rat
Isotype
Rabbit Ig
Calculated MW
55928
Antigen Region
330-357
Antigen Source
HUMAN
Target/Specificity
This FIBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-357 amino acids from the C-terminal region of human FIBB.
NCBI Accession
NP_001171670.1; NP_005132.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 80 ul
Available: In stock
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