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Kallikrein 6 Antibody (Center)

Kallikrein 6 Antibody (Center)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, FC, IHC-P
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP6325b-ev
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	Q92876
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Bio References	Christophi, G.P., et al., J. Neurochem. 91(6):1439-1449 (2004). Bayes, A., et al., Biol. Chem. 385(6):517-524 (2004). Pampalakis, G., et al., Biochem. Biophys. Res. Commun. 320(1):54-61 (2004). Ghosh, M.C., et al., Tumour Biol. 25(4):193-199 (2004). Sauter, E.R., et al., Int. J. Cancer 108(4):588-591 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB6116
Gene ID	5653
Gene Name	KLK6
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of KLK6 (arrow) using rabbit polyclonal KLK6 Antibody (L141) (Cat. #AP6325b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK6 gene.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Kallikrein 6(KLK6) Antibody (Center) (Cat. #AP6325b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Kallikrein 6(KLK6) Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	Kallikrein 6 (KLK6) Antibody (Center) Antibody (Cat. #AP6325b) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	26856
Antigen Region	126-156
Antigen Source	HUMAN
Target/Specificity	This Kallikrein 6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-156 amino acids from the Central region of human Kallikrein 6.
NCBI Accession	NP_001012982.1; NP_001012983.1; NP_002765.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/6/2024

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