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MAGEC1 Antibody (C-term)

MAGEC1 Antibody (C-term)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP6175a-ev
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	O60732
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Bio References	Jungbluth, A.A., et al., Int. J. Cancer 99(6):839-845 (2002). Chen, Y.T., et al., Proc. Natl. Acad. Sci. U.S.A. 95(12):6919-6923 (1998). Lucas, S., et al., Cancer Res. 58(4):743-752 (1998). Lim, S.H., et al., Eur. J. Haematol. 67 (5-6), 332-334 (2001).
Clonality	Polyclonal
Clone/Animal Names	RB2133/2134
Gene ID	9947
Gene Name	MAGEC1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of MAGEC1 antibody (C-term) (Cat.# AP6175a) in K562 cell line lysates (35ug/lane). MAGEC1 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	NP_005453
Isotype	Rabbit Ig
Calculated MW	123643
Antigen Region	849-880
Antigen Source	HUMAN
Target/Specificity	This MAGEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 849-880 amino acids from the C-terminal region of human MAGEC1.
NCBI Accession	NP_005453.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/6/2024

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