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TNIP3 Antibody (N-term)

TNIP3 Antibody (N-term)

Item no.	ABC-AP5598A-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ABIN3, ABIN-3, LIND, A20-binding inhibitor of NF-kappa-B activation 3, TNFAIP3-interacting protein 3, Listeria-induced gene protein, TNIP3 (HGNC:19315)
Available
Primary Accession	Q96KP6
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Bio References	Folco, E.J., et al. J. Biol. Chem. 284(38):25569-25575(2009) Verstrepen, L., et al. Biochem. Pharmacol. 78(2):105-114(2009) Wullaert, A., et al. J. Biol. Chem. 282(1):81-90(2007) Staege, H., et al. Immunogenetics 53(2):105-113(2001)
Clonality	Polyclonal
Clone/Animal Names	RB27057
Gene ID	79931
Gene Name	TNIP3 (HGNC:19315)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	TNIP3 Antibody (N-term) (Cat. #AP5598a) western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the TNIP3 antibody detected the TNIP3 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	TNIP3 Antibody (N-term) (Cat. #AP5598a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNIP3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Other Accession	NP_001122315.1; NP_079149.3
Isotype	Rabbit Ig
Calculated MW	38943
Antigen Region	74-102
Antigen Source	HUMAN
Target/Specificity	This TNIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-102 amino acids from the N-terminal region of human TNIP3.
NCBI Accession	NP_001122315.2; NP_001231693.1; NP_079149.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/6/2024

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