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TNFRSF8-Y479 Antibody

TNFRSF8-Y479 Antibody

Item no.	ABC-AP4912d-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TNFRSF8, CD30, D1S166E, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30
Available
Primary Accession	P28908
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	TNFRSF8 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
Bio References	Braun, F.K., et al. J. Invest. Dermatol. 130(3):826-840(2010) Azarpira, N., et al. Saudi J Kidney Dis Transpl 21(1):31-36(2010) Edinger, J.T., et al. Am. J. Surg. Pathol. 33(12):1860-1868(2009)
Clonality	Polyclonal
Clone/Animal Names	RB15532
Gene ID	943
Gene Name	TNFRSF8 (HGNC:11923)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of TNFRSF8-Y479 (Cat. #AP4912d) in mouse liver tissue lysates (35ug/lane). TNFRSF8 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	TNFRSF8-Y479 Antibody (Cat. #AP4912d) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TNFRSF8-Y479 Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	63747
Antigen Region	458-487
Antigen Source	HUMAN
Target/Specificity	This TNFRSF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-487 amino acids from human TNFRSF8.
NCBI Accession	NP_001234.2; NP_001268359.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/6/2024