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ABCC11 Antibody (N-term)

ABCC11 Antibody (N-term)

Item no.	ABC-AP4787a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ABCC11, MRP8, ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8
Available
Primary Accession	Q96J66
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Bio References	Martin, A., et al. J. Invest. Dermatol. 130(2):529-540(2010) J. Hum. Genet. 54(9):499-503(2009) Sato, T., et al. J. Hum. Genet. 54(7):409-413(2009)
Clonality	Polyclonal
Clone/Animal Names	RB23836
Gene ID	85320
Gene Name	ABCC11 (HGNC:14639)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of ABCC11 Antibody (N-term) (Cat. #AP4787a) in WiDr cell line lysates (35ug/lane). ABCC11 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	ABCC11 Antibody (N-term) (Cat. #AP4787a) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	154301
Antigen Region	343-372
Antigen Source	HUMAN
Target/Specificity	This ABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the N-terminal region of human ABCC11.
NCBI Accession	NP_115972.2; NP_149163.2; NP_660187.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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