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Phospho-p27Kip1(S83) Antibody

Phospho-p27Kip1(S83) Antibody

Item no.	ABC-AP3874a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Senescence Proliferation Primary Antibodies Lung Cancer Bladder Cancer Dot Blot
Type	Antibody Polyclonal
Applications	Dot blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1
Available
Primary Accession	P46527
Other Accession	NP_004055.1
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq].
Bio References	Kajihara, R., et al. Biochem. Biophys. Res. Commun. 401(3):350-355(2010) Kedde, M., et al. Nat. Cell Biol. 12(10):1014-1020(2010) Canbay, E., et al. Anticancer Res. 30(7):3093-3098(2010) Do Nascimento Borges, B., et al. In Vivo 24(4):579-582(2010) Qin, J., et al. Hepatogastroenterology 57 (99-100), 547-553 (2010) :
Gene ID	1027
Gene Name	CDKN1B
Reactivity	H
Calculated MW	22073
Antigen Source	HUMAN
Target/Specificity	This p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S83 of human p27Kip1.
NCBI Accession	NP_004055.1

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Amount: 80 ul

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