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Phospho-BAD(S74) Antibody

Phospho-BAD(S74) Antibody

Manufacturer	Abcepta
Category	Oncology Antibodies Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Autophagy Primary Antibodies Colorectal Cancer Testicular & Prostate Cancer Dot Blot
Type	Antibody Polyclonal
Specific against	other
Isotype	Ig
Applications	Dot blot
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP3777f-ev-80ul
Targets	BAD ;;BCL2;;BCL2L1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Bcl2-associated agonist of cell death, BAD, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, Bcl-xL/Bcl-2-associated death promoter, Bcl2 antagonist of cell death, BAD, BBC6, BCL2L8
Primary Accession	Q92934
Other Accession	NP_004313.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq].
Bio References	Chen, B., et al. Am. J. Physiol., Cell Physiol. 299 (5), C968-C976 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Galmiche, A., et al. Mol. Cancer Res. 8(8):1116-1125(2010) Cerioni, L., et al. Methods Mol. Biol. 648, 291-301 (2010) : Yu, B., et al. J. Exp. Clin. Cancer Res. 29, 107 (2010) :
Gene ID	572
Gene Name	BAD
Reactivity	H
Calculated MW	18392
Antigen Source	HUMAN
Target/Specificity	This BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S74 of human BAD.
NCBI Accession	NP_004313.1; NP_116784.1

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Amount: 80 ul

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