Item no. |
ABC-AP3663a-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
Dot |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
CD130, IL6ST, Interleukin-6 receptor subunit beta, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, gp130, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB |
Available |
|
Primary Accession |
P40189 |
Antigen Type |
Synthetic Peptide |
Application |
DB |
Bio Background |
IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. |
Bio References |
Lehmann, U., et.al., J. Biol. Chem. 278 (1), 661-671 (2003)Novotny-Diermayr, V., et.al., J. Biol. Chem. 277 (51), 49134-49142 (2002) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB21495 |
Gene ID |
3572 |
Gene Name |
|
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Dot blot analysis of anti-Phospho-IL6ST-Y905 Phospho-specific Pab (Cat. #AP3663a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Type image 1 |
DB |
Dilution image 1 |
1:500 |
Isotype |
Rabbit Ig |
Calculated MW |
103537 |
Antigen Source |
HUMAN |
Target/Specificity |
This IL6ST Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y905 of human IL6ST. |
NCBI Accession |
NP_001177910.1; NP_002175.2; NP_786943.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.