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Phospho-RASGRF1(S929) Antibody

Phospho-RASGRF1(S929) Antibody

Item no.	ABC-AP3496a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, Dot
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	RASGRF1, GRF1, CDC25, GNRP, Ras-specific nucleotide exchange factor CDC25, Ras-GRF1, Guanine nucleotide-releasing protein, Ras-specific guanine nucleotide-releasing factor 1
Available
Primary Accession	Q13972
Antigen Type	Synthetic Peptide
Application	WB, DB
Bio Background	RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
Bio References	Iguchi, T., Int. J. Oncol. 31 (2), 285-291 (2007) Holmes, R., Mol. Cell. Biol. 26 (24), 9564-9570 (2006)
Clonality	Polyclonal
Clone/Animal Names	RB14017
Gene ID	5923
Gene Name	RASGRF1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of lysates from A431 cell line, untreated or treated with Forskolin(50μM, 30min), using Phospho-RASGRF1(S929) Antibody(upper) or Tubulin (lower).
Type image 1	WB
Dilution image 1	1:500
Legend image 2	Dot blot analysis of anti-RASGRF1-pS929 Pab (RB14017) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Type image 2	DB
Dilution image 2	1:500
Isotype	Rabbit Ig
Calculated MW	145234
Antigen Source	HUMAN
Target/Specificity	This RASGRF1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S929 of human RASGRF1.
NCBI Accession	NP_722522.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/8/2024

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