Item no. |
ABC-AP3372a-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
Dot |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
ATF2, CREB2, Cyclic AMP-responsive element-binding protein 2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Activating transcription factor 2, HB16, cAMP response element-binding protein CRE-BP1, CREB-2, cAMP-responsive element-binding protein 2, cAMP-dependent transcription factor ATF-2, Histone acetyltransferase ATF2 |
Available |
|
Primary Accession |
P15336 |
Antigen Type |
Synthetic Peptide |
Application |
DB |
Bio Background |
ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. |
Bio References |
Kravets, A., et al., J. Biol. Chem. 279(19):19916-19923 (2004).Hong, S., et al., J. Biol. Chem. 279(17):16996-17003 (2004).Averous, J., et al., J. Biol. Chem. 279(7):5288-5297 (2004).Berger, A.J., et al., Cancer Res. 63(23):8103-8107 (2003).Wen-Sheng, W., Oncogene 22(7):955-963 (2003). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB10901 |
Gene ID |
1386 |
Gene Name |
ATF2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Dot blot analysis of Phospho-ATF2-S322 Antibody (Cat. #AP3372a) and ATF2 Non Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
Type image 1 |
DB |
Dilution image 1 |
1:500 |
Isotype |
Rabbit Ig |
Calculated MW |
54537 |
Antigen Source |
HUMAN |
Target/Specificity |
This ATF2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S322 of human ATF2. |
NCBI Accession |
NP_001243019.1; NP_001243020.1; NP_001243021.1; NP_001243022.1; NP_001243023.1; NP_001871.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.