Item no. |
ABC-AP3236a-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Rb, RB1, Retinoblastoma-associated protein, p105-Rb, pRb, pp110 |
Available |
|
Primary Accession |
P06400 |
Antigen Type |
Synthetic Peptide |
Application |
WB, IHC-P |
Bio Background |
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.[supplied by OMIM]. |
Bio References |
Dasgupta, P., et al., Mol. Cell. Biol. 24(21):9527-9541 (2004). Cui, X., et al., Hum. Pathol. 35(10):1189-1195 (2004). Borah, S., et al., J. Virol. 78(19):10336-10347 (2004). Dasgupta, P., et al., J. Biol. Chem. 279(37):38762-38769 (2004). Lohmann, D.R., et al., J. Biol. Chem. 129(1):23-28 (2004). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB7659 |
Gene ID |
5925 |
Gene Name |
RB1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of lysates from NIH/3T3 cell line, untreated or treated with UV(2h), using Phospho-RB(S612) Antibody(upper) or Tubulin (lower). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of lysates from Hela cell line, untreated or treated with UV(2h), using Phospho-RB(S612) Antibody(upper) or Tubulin (lower). |
Type image 2 |
WB |
Dilution image 2 |
1:500 |
Legend image 3 |
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma |
Type image 3 |
IHC-P |
Dilution image 3 |
1:50~100 |
Isotype |
Rabbit Ig |
Calculated MW |
106159 |
Antigen Source |
HUMAN |
Target/Specificity |
This RB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S612 of human RB. |
NCBI Accession |
NP_000312.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.