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Phospho-Bik(T33) Antibody

Phospho-Bik(T33) Antibody

Item no.	ABC-AP3042a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BIK, NBK, Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4
Available
Primary Accession	Q13323
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Bio References	Nikrad, M., et al., Mol. Cancer Ther. 4(3):443-449 (2005). Dong, F., et al., Infect. Immun. 73(3):1861-1864 (2005). Hur, J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(8):2351-2356 (2004). Gillissen, B., et al., EMBO J. 22(14):3580-3590 (2003). Arena, V., et al., Genes Chromosomes Cancer 38(1):91-96 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB7170
Gene ID	638
Gene Name	BIK
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-Bik Pab (Cat. #AP3042a) in mouse liver tissue lysate (35ug/lane). Bik(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	18016
Antigen Source	HUMAN
Target/Specificity	This Bik Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T33 of human Bik.
NCBI Accession	NP_001188.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/8/2024

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