Comparison

ENPP2 Antibody (Center)

Item no. ABC-AP2854d-ev-50ul
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Flow cytometry
Specific against other
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, ENPP2, ATX, PDNP2
Available
Primary Accession
Q13822
Antigen Type
Synthetic Peptide
Bio Background
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form.
Bio References
Kawagoe H., Soma O., Goji J., Nishimura N., Narita M., Genomics 30:380-384(1995)
Nam S.W., Clair T., Kim Y.S., McMarlin A., Cancer Res. 61:6938-6944(2001)
The MGC Project Team Genome Res. 14:2121-2127(2004)
Gene ID
5168
Gene Name
ENPP2
Reactivity
H
Calculated MW
98994
Antigen Region
377-406
Antigen Source
HUMAN
Target/Specificity
This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the Central region of human ENPP2.
NCBI Accession
NP_001035181.1; NP_001124335.1; NP_006200.3

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: Out of stock
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