Item no. |
ABC-AP2854d-ev-50ul |
Manufacturer |
Abcepta
|
Amount |
50 ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
Western Blot, Flow cytometry |
Specific against |
other |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, Autotaxin, Extracellular lysophospholipase D, LysoPLD, ENPP2, ATX, PDNP2 |
Available |
|
Primary Accession |
Q13822 |
Antigen Type |
Synthetic Peptide |
Bio Background |
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The protein is secreted and further processed to make the biologically active form. |
Bio References |
Kawagoe H., Soma O., Goji J., Nishimura N., Narita M., Genomics 30:380-384(1995) Nam S.W., Clair T., Kim Y.S., McMarlin A., Cancer Res. 61:6938-6944(2001) The MGC Project Team Genome Res. 14:2121-2127(2004) |
Gene ID |
5168 |
Gene Name |
ENPP2 |
Reactivity |
H |
Calculated MW |
98994 |
Antigen Region |
377-406 |
Antigen Source |
HUMAN |
Target/Specificity |
This ENPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the Central region of human ENPP2. |
NCBI Accession |
NP_001035181.1; NP_001124335.1; NP_006200.3 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.