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LIN28A Antibody (C-term)

LIN28A Antibody (C-term)

Item no.	ABC-AP2765b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein lin-28 homolog A, Lin-28A, Zinc finger CCHC domain-containing protein 1, LIN28A, CSDD1, LIN28, ZCCHC1
Available
Primary Accession	Q9H9Z2
Antigen Type	Synthetic Peptide
Bio Background	LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. It binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.
Bio References	Piskounova, E., J. Biol. Chem. 283 (31), 21310-21314 (2008) Wu, L., Mol. Cell. Biol. 25 (21), 9198-9208 (2005)
Gene ID	79727
Gene Name	LIN28A
Reactivity	H
Calculated MW	22743
Antigen Region	168-198
Antigen Source	HUMAN
Target/Specificity	This LIN28A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168ca.198 amino acids from the C-terminal region of human LIN28A.
NCBI Accession	NP_078950.1

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Amount: 80 ul

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