Item no. |
ABC-AP22225a-ev |
Manufacturer |
Abcepta
|
Amount |
50 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
MYPT1, PPP1R12A, MBS, Myosin phosphatase target subunit 1, Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1, Protein phosphatase myosin-binding subunit |
Available |
|
Primary Accession |
O14974 |
Antigen Type |
Synthesized Peptide |
Application |
WB |
Bio Background |
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. |
Bio References |
Takahashi N., et al.Genomics 44:150-152(1997).Guo J.H., et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.Xia D., et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.Ota T., et al.Nat. Genet. 36:40-45(2004).Scherer S.E., et al.Nature 440:346-351(2006). |
Clonality |
polyclonal |
Clone/Animal Names |
RB56565 |
Gene ID |
4659 |
Gene Name |
|
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M, Rat |
Legend image 1 |
All lanes : Anti-MYPT Antibody at 1:2000 dilutionLane 1: 293 whole cell lysateLane 2: C2C12 whole cell lysateLane 3: C6 whole cell lysateLane 4: Hela whole cell lysateLane 5: HT-29 whole cell lysateLane 6: MCF-7 whole cell lysateLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 115 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Other Accession |
Q90623; Q6DRG7; Q9DBR7; Q10728 |
Predicted |
C, Zf |
Isotype |
Rabbit Ig |
Calculated MW |
115281 |
Antigen Source |
HUMAN |
Target/Specificity |
This MYPT1 (Thr696) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 669-702 amino acids from the human MYPT1. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.