Comparison

TIGIT Antibody

Item no. ABC-AP22132a-ev-50ul
Manufacturer Abcepta
Amount 50 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3
Available
Primary Accession
Q495A1
Antigen Type
Recombinant Protein
Bio Background
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Bio References
Ota T., et al.Nat. Genet. 36:40-45(2004).
Bechtel S., et al.BMC Genomics 8:399-399(2007).
Yu X., et al.Nat. Immunol. 10:48-57(2009).
Stengel K.F., et al.Proc. Natl. Acad. Sci. U.S.A. 109:5399-5404(2012).
Gene ID
201633
Gene Name
TIGIT
Reactivity
H, M
Calculated MW
26319
Antigen Source
HUMAN
Target/Specificity
This TIGIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-142 amino acids from human TIGIT.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: Out of stock
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