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PPP1R13L Antibody (Center)

PPP1R13L Antibody (Center)

Manufacturer	Abcepta
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	Ig
Applications	Western Blot
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP21505c-ev-80ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	RelA-associated inhibitor, Inhibitor of ASPP protein, Protein iASPP, NFkB-interacting protein 1, PPP1R13B-like protein, PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Primary Accession	Q8WUF5
Bio Background	Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Bio References	Slee E.A., et al.Oncogene 23:9007-9016(2004). Herron B.J., et al.Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases. Yang J.-P., et al.J. Biol. Chem. 274:15662-15670(1999). Takada N., et al.J. Virol. 76:8019-8030(2002). Bergamaschi D., et al.Nat. Genet. 33:162-167(2003).
Gene ID	10848
Gene Name	PPP1R13L
Reactivity	H
Calculated MW	89091
Antigen Source	HUMAN
Target/Specificity	This PPP1R13L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 455-485 amino acids from the Central region of human PPP1R13L.

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Amount: 80 ul

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