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KDM6B Antibody (Center)

KDM6B Antibody (Center)

Item no.	ABC-AP21160a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Western Blot Primary Antibodies Lung Cancer Bladder Cancer Breast Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Lysine-specific demethylase 6B, 11411-, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Lysine demethylase 6B, KDM6B, JMJD3, KIAA0346
Available
Primary Accession	O15054
Bio Background	Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Bio References	Nagase T., et al.DNA Res. 4:141-150(1997). Nakajima D., et al.DNA Res. 9:99-106(2002). Zody M.C., et al.Nature 440:1045-1049(2006). Hu L.Y., et al.Gene Expr. 13:179-189(2006). De Santa F., et al.Cell 130:1083-1094(2007).
Gene ID	23135
Gene Name	KDM6B
Reactivity	M
Calculated MW	176632
Antigen Source	HUMAN
Target/Specificity	This KDM6B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 879-912 amino acids from the Central region of human KDM6B.

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Amount: 80 ul

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