Item no. |
ABC-AP21071a |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
ZO1, TJP1, Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1 |
Available |
|
Primary Accession |
Q07157 |
Application |
WB |
Bio Background |
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. |
Bio References |
Willott E., et al.Proc. Natl. Acad. Sci. U.S.A. 90:7834-7838(1993).Ota T., et al.Nat. Genet. 36:40-45(2004).Zody M.C., et al.Nature 440:671-675(2006).Cohen C.J., et al.Proc. Natl. Acad. Sci. U.S.A. 98:15191-15196(2001).D'Atri F., et al.J. Biol. Chem. 277:27757-27764(2002). |
Clonality |
Polyclonal |
Clone/Animal Names |
RB51788 |
Gene ID |
7082 |
Gene Name |
TJP1 |
Subtitle |
Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Isotype |
Rabbit Ig |
Calculated MW |
195459 |
Antigen Source |
HUMAN |
Target/Specificity |
This TJP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1328-1362 amino acids from the C-terminal region of human TJP1. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.