Comparison

TJP1 Antibody (C-term)

Item no. ABC-AP21071a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products ZO1, TJP1, Tight junction protein ZO-1, Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1
Available
Primary Accession
Q07157
Application
WB
Bio Background
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Bio References
Willott E., et al.Proc. Natl. Acad. Sci. U.S.A. 90:7834-7838(1993).
Ota T., et al.Nat. Genet. 36:40-45(2004).
Zody M.C., et al.Nature 440:671-675(2006).
Cohen C.J., et al.Proc. Natl. Acad. Sci. U.S.A. 98:15191-15196(2001).
D'Atri F., et al.J. Biol. Chem. 277:27757-27764(2002).
Clonality
Polyclonal
Clone/Animal Names
RB51788
Gene ID
7082
Gene Name
TJP1
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Western blot analysis of lysate from A431 cell line, using TJP1 Antibody (Cterm)(Cat. #AP21071a). AP21071a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
Type image 2
WB
Dilution image 2
1:1000
Isotype
Rabbit Ig
Calculated MW
195459
Antigen Source
HUMAN
Target/Specificity
This TJP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1328-1362 amino acids from the C-terminal region of human TJP1.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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