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SOX2 Antibody (C-term)

SOX2 Antibody (C-term)

Item no.	ABC-AP21034a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies Carcinoma Western Blot Primary Antibodies Interneuron Markers
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 5.1	32160702
ECLASS 6.1	32160702
ECLASS 8.0	32160702
ECLASS 9.0	32160702
ECLASS 10.0.1	32160702
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Transcription factor SOX-2, SOX2
Available
Primary Accession	P48431
Other Accession	P48430; P54231
Bio Background	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Bio References	Stevanovic M., et al.Mamm. Genome 5:640-642(1994). Sadler L.A., et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases. Fantes J., et al.Nat. Genet. 33:461-463(2003). Takahashi K., et al.Cell 131:861-872(2007). Rigbolt K.T., et al.Sci. Signal. 4:RS3-RS3(2011).
Gene ID	6657
Gene Name	SOX2
Reactivity	H, M
Predicted	C, Sh
Calculated MW	34310
Antigen Source	HUMAN
Target/Specificity	This SOX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 282-316 amino acids from the C-terminal region of human SOX2.

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Amount: 80 ul

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