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EWSR1 Antibody (Center)

EWSR1 Antibody (Center)

Item no.	ABC-AP20981a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Sarcoma Western Blot Primary Antibodies Bone Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Available
Primary Accession	Q01844
Other Accession	Q61545
Bio Background	Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
Bio References	Delattre O., et al.Nature 359:162-165(1992). Plougastel B., et al.Genomics 18:609-615(1993). Zucman-Rossi J., et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases. Collins J.E., et al.Genome Biol. 5:R84.1-R84.11(2004). Ota T., et al.Nat. Genet. 36:40-45(2004).
Gene ID	2130
Gene Name	EWSR1
Reactivity	M
Calculated MW	68478
Antigen Source	HUMAN
Target/Specificity	This EWSR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 328-362 amino acids from the Central region of human EWSR1.

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Amount: 80 ul

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