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MME Antibody (Center)

MME Antibody (Center)

Item no.	ABC-AP20692c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies Hematology Leukemia Lymphoma Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies Heart & Blood Cancer Renal Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN
Available
Primary Accession	P08473
Other Accession	P08049
Bio Background	Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV- inducible elastase activity toward skin preelastic and elastic fibers.
Bio References	Letarte M., et al.J. Exp. Med. 168:1247-1253(1988). Shipp M.A., et al.Proc. Natl. Acad. Sci. U.S.A. 85:4819-4823(1988). D'Adamio L., et al.Proc. Natl. Acad. Sci. U.S.A. 86:7103-7107(1989). Ota T., et al.Nat. Genet. 36:40-45(2004). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Gene ID	4311
Gene Name	MME
Reactivity	H, M, Rat
Predicted	Rb
Calculated MW	85514
Antigen Source	HUMAN
Target/Specificity	This MME antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 492-525 amino acids from the Central region of human MME.

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Amount: 80 ul

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