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RRM1 Antibody (N-term)

RRM1 Antibody (N-term)

Manufacturer	Abcepta
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	Ig
Applications	Western Blot
Amount	80 ul
Host	Rabbit
Item no.	ABC-AP20081a-ev-80ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Ribonucleoside-diphosphate reductase large subunit, Ribonucleoside-diphosphate reductase subunit M1, Ribonucleotide reductase large subunit, RRM1, RR1
Primary Accession	P23921
Other Accession	P07742; NP_001024.1
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Bio References	Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Vinolas, N., et al. Lung Cancer (2010) In press : Niida, H., et al. Genes Dev. 24(4):333-338(2010) Dong, S., et al. J Hematol Oncol 3, 10 (2010) :
Gene ID	6240
Gene Name	RRM1
Reactivity	H
Predicted	M
Calculated MW	90070
Antigen Region	71-100
Antigen Source	HUMAN
Target/Specificity	This RRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human RRM1.
NCBI Accession	NP_001024.1

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Amount: 80 ul

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