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Mouse Casc5 Antibody (C-term)

Mouse Casc5 Antibody (C-term)

Item no.	ABC-AP19227b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Available
Primary Accession	Q66JQ7
Antigen Type	Synthetic Peptide
Bio Background	Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).
Gene Name	Knl1 {ECO:0000312\|MGI:MGI:1923714}
Reactivity	M
Antigen Region	1557-1583
Antigen Source	MOUSE
Target/Specificity	This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.

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Amount: 80 ul

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