BEST3 Antibody (N-term)

Synthetic Peptide

BEST3 belongs to the bestrophin family of anion channels,
which includes BEST1 (MIM 607854), the gene mutant in vitelliform
macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes,
BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are
transmembrane (TM) proteins that share a homology region containing
a high content of aromatic residues, including an invariant
arg-phe-pro (RFP) motif. The bestrophin genes share a conserved
gene structure, with almost identical sizes of the 8 RFP-TM
domain-encoding exons and highly conserved exon-intron boundaries.
Each of the 4 bestrophin genes has a unique 3-prime end of variable
length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al.,
2003 [PubMed 12907679]).

Polyclonal

144453

Affinity Purified Rabbit Polyclonal Antibody (Pab)

BEST3 Antibody (N-term) (Cat. #AP19190a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the BEST3 antibody detected the BEST3 protein (arrow).

1:1000

Rabbit Ig

40-68

This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3.