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RENT1 Antibody (N-term E22)

RENT1 Antibody (N-term E22)

Item no.	ABC-AP1905a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Carcinoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Regulator of nonsense transcripts 1, 364-, ATP-dependent helicase RENT1, Nonsense mRNA reducing factor 1, NORF1, Up-frameshift suppressor 1 homolog, hUpf1, UPF1, KIAA0221, RENT1
Available
Primary Accession	Q92900
Other Accession	Q9EPU0
Antigen Type	Synthetic Peptide
Bio Background	RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.
Bio References	Ohnishi, T., et al., Mol. Cell 12(5):1187-1200 (2003). Lykke-Andersen, J., Mol. Cell. Biol. 22(23):8114-8121 (2002). Carastro, L.M., et al., Nucleic Acids Res. 30(10):2232-2243 (2002). Mendell, J.T., et al., Science 298(5592):419-422 (2002). Serin, G., et al., Mol. Cell. Biol. 21(1):209-223 (2001).
Gene ID	5976
Gene Name	UPF1
Reactivity	H
Predicted	M
Calculated MW	124345
Antigen Region	7-37
Antigen Source	HUMAN
Target/Specificity	This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human RENT1.
NCBI Accession	NP_002902.2

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Amount: 80 ul

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