Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
other |
Isotype |
Ig |
Applications |
Western Blot |
Amount |
80 ul |
Host |
Rabbit |
Item no. |
ABC-AP19028a-ev-80ul |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Alias |
Pregnancy-specific beta-1-glycoprotein 4, PS-beta-G-4, PSBG-4, Pregnancy-specific glycoprotein 4, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PSG4, CGM4, PSG9 |
Primary Accession |
Q00888 |
Other Accession |
NP_002771.2 |
Antigen Type |
Synthetic Peptide |
Bio Background |
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390). |
Bio References |
Kimoto, Y. Mol. Gen. Genet. 258(3):233-239(1998) Teglund, S., et al. Biochem. Biophys. Res. Commun. 211(2):656-664(1995) Teglund, S., et al. Genomics 23(3):669-684(1994) Olsen, A., et al. Genomics 23(3):659-668(1994) Chan, W.Y., et al. Mol. Cell. Biochem. 106(2):161-170(1991) |
Gene ID |
5672 |
Gene Name |
PSG4 |
Reactivity |
H |
Calculated MW |
47113 |
Antigen Region |
73-100 |
Antigen Source |
HUMAN |
Target/Specificity |
This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4. |
NCBI Accession |
NP_002771.2; NP_998798.1 |
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