HOXA1 Antibody (N-term)

NP_005513.1

In vertebrates, the genes encoding the class of
transcription factors called homeobox genes are found in clusters
named A, B, C, and D on four separate chromosomes. Expression of
these proteins is spatially and temporally regulated during
embryonic development. This gene is part of the A cluster on
chromosome 7 and encodes a DNA-binding transcription factor which
may regulate gene expression, morphogenesis, and differentiation.
The encoded protein may be involved in the placement of hindbrain
segments in the proper location along the anterior-posterior axis
during development. Two transcript variants encoding two different
isoforms have been found for this gene, with only one of the
isoforms containing the homeodomain region.

3198

H, M

9-35

This HOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-35 amino acids from the N-terminal region of human HOXA1.