Alias |
POU domain, class 2, transcription factor 1, NF-A1, Octamer-binding protein 1, Oct-1, Octamer-binding transcription factor 1, OTF-1, POU2F1, OCT1, OTF1 |
Bio Background |
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT. |
Bio References |
Vuzman, D., et al. Biophys. J. 99(4):1202-1211(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Davila, S., et al. Genes Immun. 11(3):232-238(2010) Laurent, B., et al. Blood 115(3):687-695(2010) Becker, M.L., et al. Pharmacogenet. Genomics 20(1):38-44(2010) |