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GABARAP Antibody (N-term)

GABARAP Antibody (N-term)

Item no.	ABC-AP1821a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein, MM46, GABARAP, FLC3B
Available
Primary Accession	O95166
Other Accession	P60517; Q8MK68; Q9DCD6; Q9GJW7
Antigen Type	Synthetic Peptide
Bio Background	Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABARAP is GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton.
Bio References	References for protein: 1.Nemos, C., et al., Brain Res. Mol. Brain Res. 119(2):216-219 (2003). 2.Stangler, T., et al., J. Biol. Chem. 277(16):13363-13366 (2002). 3.Knight, D., et al., J. Biol. Chem. 277(7):5556-5561 (2002). 4.Tanida, I., et al., J. Biol. Chem. 277(16):13739-13744 (2002). 5.Harris, R., et al., J. Biomol. NMR 21(2):185-186 (2001). References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973)." Determinants for the establishment of permanent tissue culture lines from human gliomas". Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J., Westermark B. (1978)." Properties of Human Malignant Glioma Cells in Vitro". Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.; Kohli L.; Klocke B.J.; Roth K.A.(2010). "Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent". Neuro Oncol. 12(5): 473-481.[ PMID: 20406898].
Gene ID	11337
Gene Name	GABARAP
Reactivity	H, M, Rat
Predicted	B, Rb
Calculated MW	13918
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This GABARAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids of human GABARAP.
NCBI Accession	NP_009209.1

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Amount: 80 ul

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