Item no. |
ABC-AP18214C-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
PCDHA1, Protocadherin alpha-1, PCDH-alpha-1 |
Available |
|
Primary Accession |
Q9Y5I3 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
This gene is a member of the protocadherin alpha genecluster, one of three related gene clusters tandemly linked onchromosome five that demonstrate an unusual genomic organizationsimilar to that of B-cell and T-cell receptor gene clusters. Thealpha gene cluster is composed of 15 cadherin superfamily genesrelated to the mouse CNR genes and consists of 13 highly similarand 2 more distantly related coding sequences. The tandem array of15 N-terminal exons, or variable exons, are followed by downstreamC-terminal exons, or constant exons, which are shared by all genesin the cluster. The large, uninterrupted N-terminal exons eachencode six cadherin ectodomains while the C-terminal exons encodethe cytoplasmic domain. These neural cadherin-like cell adhesionproteins are integral plasma membrane proteins that most likelyplay a critical role in the establishment and function of specificcell-cell connections in the brain. Alternative splicing has beenobserved and additional variants have been suggested but theirfull-length nature has yet to be determined. |
Bio References |
Lachman, H.M., et al. Psychiatr. Genet. 18(3):110-115(2008)Wu, C., et al. Proteomics 7(11):1775-1785(2007)Wu, Q., et al. Genome Res. 11(3):389-404(2001)Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB32960 |
Gene ID |
56147 |
Gene Name |
PCDHA1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
PCDHA1 Antibody (Center) (Cat. #AP18214c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PCDHA1 antibody detected the PCDHA1 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_061723.1 |
Isotype |
Rabbit Ig |
Calculated MW |
102952 |
Antigen Region |
288-316 |
Antigen Source |
HUMAN |
Target/Specificity |
This PCDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PCDHA1. |
NCBI Accession |
NP_061723.1; NP_113598.1; NP_113599.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.