« Back
Home /
FZD7 Antibody (Center)

FZD7 Antibody (Center)

Item no.	ABC-AP18021c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FZD7, Frizzled-7, FzE3, Fz-7, hFz7
Available
Primary Accession	O75084
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Bio References	Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Vincan, E., et al. Dev. Dyn. 239(1):311-317(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009) Ueno, K., et al. Br. J. Cancer 101(8):1374-1381(2009)
Clonality	Polyclonal
Clone/Animal Names	RB25727
Gene ID	8324
Gene Name	FZD7
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	FZD7 Antibody (Center) (Cat. #AP18021c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FZD7 antibody detected the FZD7 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q61090; O57329; NP_003498.1
Predicted	C, M
Isotype	Rabbit IgG
Calculated MW	63620
Antigen Region	202-229
Antigen Source	HUMAN
Target/Specificity	This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.
NCBI Accession	NP_003498.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP18021c-ev-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 80 ul

available

Delivery expected until 9/6/2024