Item no. |
ABC-AP17801c-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
LPXN, LDLP, Leupaxin |
Available |
|
Primary Accession |
O60711 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The product encoded by this gene is preferentiallyexpressed in hematopoietic cells and belongs to the paxillinprotein family. Similar to other members of thisfocal-adhesion-associated adaptor-protein family, it has fourleucine-rich LD-motifs in the N-terminus and four LIM domains inthe C-terminus. It may function in cell type-specific signaling byassociating with PYK2, a member of focal adhesion kinase family. Asa substrate for a tyrosine kinase in lymphoid cells, this proteinmay also function in, and be regulated by, tyrosine kinaseactivity. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Tanaka, T., et al. Cancer Sci. 101(2):363-368(2010)Dai, H.P., et al. Genes Chromosomes Cancer 48(12):1027-1036(2009)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Sundberg-Smith, L.J., et al. Circ. Res. 102(12):1502-1511(2008) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB37022 |
Gene ID |
9404 |
Gene Name |
LPXN |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
LPXN Antibody (Center) (Cat. #AP17801c) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the LPXN antibody detected the LPXN protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
Western blot analysis of LPXN (arrow) using rabbit polyclonal LPXN Antibody (Center) (Cat. #AP17801c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LPXN gene. |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Other Accession |
Q99N69; NP_004802.1 |
Isotype |
Rabbit Ig |
Calculated MW |
43332 |
Antigen Region |
229-257 |
Antigen Source |
HUMAN |
Target/Specificity |
This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN. |
NCBI Accession |
NP_001137467.1; NP_004802.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.