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IQCB1 Antibody (Center)

IQCB1 Antibody (Center)

Item no.	ABC-AP17066C
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IQCB1, KIAA0036, NPHP5, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ
Available
Primary Accession	Q15051
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.
Bio References	Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009) Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008) Luo, X., et al. Cancer Res. 65(23):10725-10733(2005) le Maire, A., et al. Proteins 59(2):347-355(2005) Mollet, G., et al. Hum. Mol. Genet. 14(5):645-656(2005)
Clonality	Polyclonal
Clone/Animal Names	RB36926
Gene ID	9657
Gene Name	IQCB1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	IQCB1 Antibody (Center) (Cat. #AP17066c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the IQCB1 antibody detected the IQCB1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_001018865.2; NP_001018864.2
Isotype	Rabbit Ig
Calculated MW	68929
Antigen Region	384-411
Antigen Source	HUMAN
Target/Specificity	This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
NCBI Accession	NP_001018864.2; NP_001018865.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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