Bio Background |
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq]. |
Bio References |
Newton-Cheh, C., et al. Nat. Genet. (2009) In press : Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006) Beder, L.B., et al. J. Cancer Res. Clin. Oncol. 132(1):19-27(2006) Aspenstrom, P., et al. Biochem. J. 377 (PT 2), 327-337 (2004) : Ramos, S., et al. Gene 298(2):147-157(2002) |