Item no. |
ABC-AP16759c-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Keratin, KRT3, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, Keratin-3, Type-II keratin Kb3, K3, CK-3 |
Available |
|
Primary Accession |
P12035 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. This type II cytokeratin is specificallyexpressed in the corneal epithelium with family member KRT12 andmutations in these genes have been associated with Meesmann'sCorneal Dystrophy. The type II cytokeratins are clustered in aregion of chromosome 12q12-q13. |
Bio References |
Szaflik, J.P., et al. Mol. Vis. 14, 1713-1718 (2008) :Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)Chen, Y.T., et al. Cornea 24(8):928-932(2005)Rogers, M.A., et al. J. Invest. Dermatol. 124(3):536-544(2005)Irvine, A.D., et al. Nat. Genet. 16(2):184-187(1997) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB36551 |
Gene ID |
3850 |
Gene Name |
KRT3 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
KRT3 Antibody (Center) (Cat. #AP16759c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the KRT3 antibody detected the KRT3 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_476429.2 |
Isotype |
Rabbit Ig |
Calculated MW |
64417 |
Antigen Region |
414-441 |
Antigen Source |
HUMAN |
Target/Specificity |
This KRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3. |
NCBI Accession |
NP_476429.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.