Item no. |
ABC-AP16746a |
Manufacturer |
Abcepta
|
Amount |
400 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
Ubiquitin-processing protease UBP-M, Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}, 341912 {ECO:0000255|HAMAP-Rule:MF_03062}, Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}, Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}, Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062}, USP16 {ECO:0000255|HAMAP-Rule:MF_03062} |
Available |
|
Primary Accession |
Q9Y5T5 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
This gene encodes a deubiquitinating enzyme that isphosphorylated at the onset of mitosis and then dephosphorylated atthe metaphase/anaphase transition. It can deubiquitinate H2A, oneof two major ubiquitinated proteins of chromatin, in vitro and amutant form of the protein was shown to block cell division.Alternate transcriptional splice variants, encoding differentisoforms, have been characterized. |
Bio References |
Gelsi-Boyer, V., et al. BMC Cancer 8, 299 (2008) :Joo, H.Y., et al. Nature 449(7165):1068-1072(2007)Pai, M.T., et al. J. Mol. Biol. 370(2):290-302(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB36395 |
Gene ID |
10600 |
Gene Name |
USP16 {ECO:0000255|HAMAP-Rule:MF_03062} |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
USP16 Antibody (N-term) (Cat. #AP16746a) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the USP16 antibody detected the USP16 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
Q4R6X7; NP_001001992.1; NP_001027582.1 |
Predicted |
Pr |
Isotype |
Rabbit Ig |
Calculated MW |
93570 |
Antigen Region |
132-160 |
Antigen Source |
HUMAN |
Target/Specificity |
This USP16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human USP16. |
NCBI Accession |
NP_001001992.1; NP_001027582.1; NP_006438.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.