Comparison

NACC2 Antibody (C-term)

Item no. ABC-AP16720b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Nucleus accumbens-associated protein 2, NAC-2, BTB/POZ domain-containing protein 14A, Repressor with BTB domain and BEN domain, NACC2, BTBD14A, NAC2, RBB
Available
Primary Accession
Q96BF6
Other Accession
NP_653254.1
Antigen Type
Synthetic Peptide
Bio Background
BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
Bio References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Gene Name
NACC2
Reactivity
H
Antigen Region
473-502
Antigen Source
HUMAN
Target/Specificity
This NACC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2.
NCBI Accession
NP_653254.1

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Amount: 80 ul
Available: Out of stock
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