Item no. |
ABC-AP16115b-ev |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Primary |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Specific against |
other |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Similar products |
SGCD, Delta-sarcoglycan, 35 kDa dystrophin-associated glycoprotein, 35DAG, Delta-SG |
Available |
|
Primary Accession |
Q92629 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
The protein encoded by this gene is one of the four knowncomponents of the sarcoglycan complex, which is a subcomplex of thedystrophin-glycoprotein complex (DGC). DGC forms a link between theF-actin cytoskeleton and the extracellular matrix. This protein isexpressed most abundantly in skeletal and cardiac muscle. Mutationsin this gene have been associated with autosomal recessivelimb-girdle muscular dystrophy and dilated cardiomyopathy.Alternatively spliced transcript variants encoding distinctisoforms have been observed for this gene. |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)Ordonez-Razo, R.M., et al. Genet Test Mol Biomarkers 14(2):237-240(2010)Lin, W.Y., et al. BMC Res Notes 3, 26 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB35027 |
Gene ID |
6444 |
Gene Name |
SGCD |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
M |
Legend image 1 |
SGCD Antibody (C-term) (Cat. #AP16115b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SGCD antibody detected the SGCD protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Other Accession |
NP_001121681.1; NP_000328.2; NP_758447.1 |
Isotype |
Rabbit Ig |
Calculated MW |
32071 |
Antigen Region |
232-261 |
Antigen Source |
HUMAN |
Target/Specificity |
This SGCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human SGCD. |
NCBI Accession |
NP_000328.2; NP_001121681.1; NP_758447.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.