FOLR2 Antibody (N-term)

Synthetic Peptide

The protein encoded by this gene is a member of the folate
receptor (FOLR) family, and these genes exist in a cluster on
chromosome 11. Members of this gene family have a high affinity for
folic acid and for several reduced folic acid derivatives, and they
mediate delivery of 5-methyltetrahydrofolate to the interior of
cells. This protein has a 68% and 79% sequence homology with the
FOLR1 and FOLR3 proteins, respectively. Although this protein was
originally thought to be specific to placenta, it can also exist in
other tissues, and it may play a role in the transport of
methotrexate in synovial macrophages in rheumatoid arthritis
patients. Multiple transcript variants that encode the same protein
have been found for this gene.

Polyclonal

2350

Affinity Purified Rabbit Polyclonal Antibody (Pab)

FOLR2 Antibody (N-term) (Cat. #AP16014a) western blot analysis in MDA-MB453, NCI-H460 cell line lysates (35ug/lane).This demonstrates the FOLR2 antibody detected the FOLR2 protein (arrow).

1:1000

M

29280

HUMAN

NP_000794.3; NP_001107006.1; NP_001107007.1; NP_001107008.1